iPSC-Derived Monocytes With Media

$1,650.00

SKU ASE-9745-1 Categories , ,

iPSC-Derived Monocytes

With Media

We use our efficient, integration-free, small-molecule-based method to differentiate high-quality monocytes from human iPSCs. The differentiated monocytes recapitulate the phenotype and functional parameters of primary and in vivo monocytes.

We provide monocytes differentiated from an integration-free, control human iPSC line (ASE-9211), reprogrammed from the fibroblasts of an African American male donor. These high-purity (>90%) cells express high levels of monocyte biomarkers CD14.

These iPSC-differentiated monocytes can be used as control lines to compare the phenotype and functionality of patient-derived, genome-edited iPSC-derived monocytes for drug screening applications.

Figure 1. Immunostaining of ASE-9745 iPSC-derived monocytes for monocyte biomarkers. Cryopreserved monocytes, differentiated from Applied StemCell’s control iPSC line, ASE-9211, were recovered in monocyte culture media. The cells were stained with monocyte markers, CD14.

Donor information

Table Header Table Header
Age
Neonate
Gender
Male
Ethnicity
African American
Tissue source
Dermal fibroblasts
Reprogramming method
Episomal
Culture conditions
Feeder-free

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