Off-the-shelf Humanized Mouse Models

Applied StemCell, a long-standing leader in custom mouse model engineering, offers 2,000+ off-the-shelf proprietary, genetically engineered mouse models (GEMM) that are research-ready and can be directly used in gene function, drug screening, and human disease research.

• Humanized immune checkpoint models with single, double or triple-target modifications in PD1, PD-L1, CTLA4, and other genes
• Cytokine receptor-related models with fluorescent tags for live-imaging studies
• Immunodeficient models for immune system and cancer studies
• Human disease models with knockout, knock-in, conditional knockout mutations
• Cre recombinase, reporter genes, Cas9-expressing models, and more
• >30 fluorescent-labeled tumor cell lines for use in in vitro experiments and tumor studies