C57BL/6J-Lyz2em1(2A-CreERT2-WPRE-pA)Asc

SKU ASKI-18018 Categories Cre Mouse Models, Mouse Models, Other Gene Edited Mouse Models (KO, CKO), Products

Strain Information

Table Header	Table Header
Catalog Number	ASKI-18018
Model Name	Lyz2-(2A-CreERT2-WPRE-pA)
Strain Name	ASKI-18018
GENE Synonyms	Lys; Lzm; Lzp; Lysm; Lyzs; Lyzf2; Lzm-s1; AI326280
Ensembl ID	ENSMUSG00000069516
MGI ID	96897
NCBI ID	17105
Background	C57BL/6J
Coat Color	Black
Mutation Type	Knock-in
Model Type	C57BL/6J-Lyz2em1(2A-CreERT2-WPRE-pA)Smoc
Research Application	Immunotherapy

A 2A-CreERT2-WPRE-pA coexpression cassette is inserted befor the stop codon of mouse Lyz2 gene via homologous recombination to establish a tamoxifen inducible Lyz2-CreERT2 tool stain. This strain can be used to knockout target gene in Lyz2+ cells after tamoxifen treatment when crossed with mice which carry loxp sites flanking target gene.

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